RELEASE OF ACETYLCHOLINE BY VAGAL STIMULATION
نویسندگان
چکیده
منابع مشابه
Angiotensin II attenuates myocardial interstitial acetylcholine release in response to vagal stimulation.
Although ANG II exerts a variety of effects on the cardiovascular system, its effects on the peripheral parasympathetic neurotransmission have only been evaluated by changes in heart rate (an effect on the sinus node). To elucidate the effect of ANG II on the parasympathetic neurotransmission in the left ventricle, we measured myocardial interstitial ACh release in response to vagal stimulation...
متن کاملAuricular fibrillation induced and maintained in animals by acetylcholine or vagal stimulation.
Animals pretreated with appropriate closes of anticholinesterase agents develop auricular flutter and fibrillation following injection of acetylcholine or vagal stimulation. Depression of normal sinoauricular nodal function facilitates induction of fibrillation. During fibrillation, additional injections of acetylcholine, or vagal stimulation, increase the rate of fibrillation. Atropine in smal...
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Stimulation of ciliary cells through muscarinic receptors leads to a strong biphasic enhancement of ciliary beat frequency (CBF). The main goal of this work is to delineate the chain of molecular events that lead to the enhancement of CBF induced by acetylcholine (ACh). Here we show that the Ca(2+), cGMP, and cAMP signaling pathways are intimately interconnected in the process of cholinergic ci...
متن کاملVagal Stimulation in Dogs
We determined the effects of changing the spatial dispersion of acetylcholine release on the phase-dependent chronotropic responses to vagal stimulation in anesthetized dogs. We stimulated the vagus nerves with one brief burst of electrical pulses each cardiac cycle, and we changed the timing of the stimulus by a small, constant amount each cardiac cycle to scan the entire cycle. To vary the he...
متن کاملAdrenergic inhibition of endogenous acetylcholine release on postganglionic cardiac vagal nerve terminals.
OBJECTIVE The aim was to examine the adrenergic modulation of endogenous acetylcholine (ACh) release from vagal nerve terminals in the in vivo heart. METHODS Using dialysis technique in anesthetized cats, we investigated the influence of exogenous noradrenaline on dialysate ACh response. Dialysis probes were implanted in the left ventricular myocardium and perfused with Krebs-Henseleit buffer...
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ژورنال
عنوان ژورنال: Quarterly Journal of Experimental Physiology and Cognate Medical Sciences
سال: 1938
ISSN: 0033-5541
DOI: 10.1113/expphysiol.1938.sp000773